Effect of Adding Sildenafil to Clomiphene Citrate versus Clomiphene Citrate alone on Endometrium in Unexplained Infertility: Cross-Sectional, Non-Randomized Study

P-227: The Survey on Endometrial Thickness and Echo Pattern Changes in Consecutive Cycles of Clomiphene Citrate Therapy in Infertile Women

Background: One of the most common causes of infertility in women is ovulatory dysfunction (PCOS) and the choice of treatment is clomiphene citrate. One of the mechanism of dichotomy between the rate of ovulation and pregnancy is anti estrogenic effects of clomiphene citrate on endometrium. According to its long half life, the anti estrogenic effects probably exacerbate in consecutive cycles. W...

Adding sildenafil vaginal gel to clomiphene citrate in infertile women with prior clomiphene citrate failure due to thin endometrium: a prospective self-controlled clinical trial

We aimed to investigate the effect of adding sildenafil vaginal gel to clomiphene citrate (CC) in infertile women with prior CC failure. METHODS This is a self- controlled clinical trial. Women with CC failure (in prior 5 cycles) and thin endometrium were recruited (N = 42). In their 6th (CC only) cycle, women continued on CC 100 mg/ day for 5 days, and had measurement of endometrial thicknes...

Does Adding Dexamethasone to Clomiphene Citrate Improve Ovulation in PCOS Patients? A Triple - Blind Randomized Clinical Trial Study

Are Uterine and Ovarian Artery Doppler Velocimetry Values Good Pregnancy Predictors in Clomiphene Citrate Cycles?

Background We conducted this prospective study to evaluate the prognostic significance of uterine and ovarian artery Doppler velocimetry in clomiphene citrate (CC) cycles. MaterialsAndMethods A total of 80 patients with unexplained infertility were given 100 mg/day of CC from day 3 to day 7 of their cycles in this current prospective study. On cycle day 3, before administration of CC, each pati...

Effects of Metformin on Ovulation and Pregnancy Rate in Women with Clomiphene Resistant Poly Cystic Ovary Syndrome

Background To evaluate the effect of metformin on ovulation and pregnancy rate in clomiphene citrate resistant women with polycystic ovary syndrome (PCOS). MaterialsAndMethods In this clinical trial each patient, regarding her previous resistance to Clomiphene, served as her own control. A total of 35 clomiphene citrate resistant PCOS patients, referring to Royan institute were studied. Clomiph...